| Effect and Comparison of Sodium Butyrate and Trichostatin A on the Proliferation/Differentiation of K562 |
| |
| 作者姓名： | 李春蕊 刘文励 孟凡凯 黄伟 周剑锋 孙汉英 冯永东 |
| |
| 作者单位： | Department of Hematology，Department of Hematology，Department of Hematology，Department of Hematology，Department of Hematology，Department of Hematology，Department of Hematology Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030 |
| |
| 基金项目： | ThisprojectwassupportedbyagrantfromNationalNaturalSciencesFoundationofChina (No 30 0 70 32 6 ) |
| |
| 摘 要： | Thereisampleevidence ,bothinvitroandinvivo,thatHDACinhibitorsblocktheenzymaticac tivityofdeacetylasesandinducehyperacetylationofhistones1] Furthermore ,aplethoraofculturedtu morcellshasbeentestedforsusceptibilitytoHDACinhibition UpontreatmentwithHDACinhibitors ,thesecellsshowsignsofapoptosis ,growtharrest,differentiationandaltered geneexpression HDACinhibitorsare potentially promisingcandidatedrugsfordifferentiationtherapyofcancer ButyratewasthefirstHDACinhibitortobei dentified2 ] a…
|
| 收稿时间： | 11 March 2003 |
Effect and comparison of sodium butyrate and trichostatin a on the proliferation/differentiation of K562 |
| |
| Li?Chunrui,Liu?Wenli,Meng?Fankai,Huang?Wei,Zhou?Jianfeng,Sun?Hanying,Feng?Yongdong.Effect and Comparison of Sodium Butyrate and Trichostatin A on the Proliferation/Differentiation of K562[J].Journal of Zuazhong University of Science and Technology: Medical Edition,2003,23(3):249-253. |
| |
| Authors: | Li Chunrui Liu Wenli Meng Fankai Huang Wei Zhou Jianfeng Sun Hanying Feng Yongdong |
| |
| Institution: | Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030 |
| |
| Abstract: | |
| |
| Keywords: | sodium butyrate cyclin D p21 trichostatin A |
| 本文献已被 CNKI 万方数据 SpringerLink 等数据库收录！ |
