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Correlation between Cyclin A Gene Expression in Adult Patients with Acute Leukemia and Drug Resistance
引用本文:马劼,徐世荣,赖永榕,卢玉英,姚尔固. Correlation between Cyclin A Gene Expression in Adult Patients with Acute Leukemia and Drug Resistance[J]. 华中科技大学学报(医学英德文版), 2003, 23(3): 245-248. DOI: 10.1007/BF02829504
作者姓名:马劼  徐世荣  赖永榕  卢玉英  姚尔固
作者单位:Department of Hematology,Department of Hematology,Department of Hematology,Department of Hematology,Department of Hematology Second Hospital,Hebei Medical University,Shijiazhuang 050000,Second Hospital,Hebei Medical University,Shijiazhuang 050000,First Hospital,Guangxi Medical University,Nanning,530021,First Hospital,Guangxi Medical University,Nanning,530021,Second Hospital,Hebei Medical University,Shijiazhuang 050000
基金项目:ThisprojectwassupportedbygrantsfromHebeiCommitteeofScienceandTechnology (No.2 0 0 1 0 13761229)andGuangxiBureauofPublicHealth (No .Z2 0 0 10 19)
摘    要:Adultacuteleukemia (AL)isoneofthemostcommonmalignanttumorsofhematology .Withtherecentprogressinchemotherapyandsupportivether apy ,theremissionandsurvivalrateinALhavebeenmarkedlyimproved .However ,drugresistanceandrelapsearestillimportantfactorsaffectinglongsur vivalofthese patients .Theabnormalregulationofcellcycleisanotherfactorthatcannotbeignoredex ceptformultipledrugresistance (MDR) .WedetectcyclinA ,multidrugresistantgene (mdrl) ,topoiso meraseⅡα(TopⅡα)andbcl 2inadultpatientswithA…

收稿时间:2002-09-29

Correlation between cyclin A gene expression in adult patients with acute leukemia and drug resistance
Jie,Ma,Shirong,Xu,Yongrong,Lai,Yuying,Lu,Ergu,Yao. Correlation between cyclin A gene expression in adult patients with acute leukemia and drug resistance[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 2003, 23(3): 245-248. DOI: 10.1007/BF02829504
Authors:Jie  Ma  Shirong  Xu  Yongrong  Lai  Yuying  Lu  Ergu  Yao
Affiliation:1. Department of Hematology, Second Hospital, Hebei Medical University, Shijiazhuang 050000
2. Department of Hematology, First Hospital, Guangxi Medical University, Nanning, 530021
Abstract:
Keywords:acute leukemia  cyclin A  drug resistance   multiple
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