ICU感染性休克病死危险因素及相应的临床治疗措施分析

目的：对ICU感染性休克病死率、病死危险因素与相应临床治疗措施进行分析。方法：对96例感染性休克患者展开回顾性分析，利用单因素与多因素Logistic回归分析方法对患者病死危险因素展开分析。结果：96例患者病死率为57.29%；单因素分析结果显示，在感染性休克患者中，存活组与死亡组在APACHEⅡ评分、年龄、SIRS数目、血液感染、平均动脉压及白蛋白、24 h尿量与MODS数目8个因素差异有统计学意义（P〈0.05）；多因素Logistic回归分析结果表明，白蛋白、SIRS数目、APACHEⅡ评分与MODS数目是导致ICU感染性休克患者病死的独立危险因素。结论：在对ICU感染性休克展开治疗时，对炎症反应进行积极调控，以去除病因为基础展开综合治疗，可有效降低该疾病病死率。

Study on Risk Factors of Fatality Caused by Septic Shock in ICU and Corresponding Clinical Therapeutic Measures

Objective： To analyze the fatality rate caused by septic shock, risk factors for fatality and the corresponding clinical therapeutic measures in ICU.Method： Ninety-six cases of patients with septic shock were analyzed retrospectively, and the risk factors for fatality of patients were analyzed with single-factor and multiple-factor Logistic regression analysis method.Result： The case fatality rate of the 96 cases of patients was 57.29%; The results of single-factor analysis showed that the APACHEⅡ score, age, number of SIRS, blood infection, 24 h urinary amount, mean arterial pressure and albumin and the number of MODS of the survival group and the fatality group in the patients with septic shock had significant difference （P〈0.05）. The multiple-factor Logistic regression analysis showed that Albumin, number of SIRS, APACHE Ⅱ score and the number of MODS were the risk factors causing fatality of patients with septic shock in the ICU.Conclusion： For patients with septic shock in ICU, active control measures to inflammatory responses and comprehensive treatment on the basis of pathogenesis removal can help reduce the fatality rate during treatment.