|
|||||
|
|
| 葡萄糖酸锗对小鼠Lewis肺癌放射增敏效应实验研究 | |
| 引用本文： | 陈延治!110001沈阳,吴荣!110001沈阳,张银娟!110001沈阳,张春生!110001沈阳. 葡萄糖酸锗对小鼠Lewis肺癌放射增敏效应实验研究[J]. 中华放射肿瘤学杂志, 1995, 0(4) |
| 作者姓名： | 陈延治!110001沈阳 吴荣!110001沈阳 张银娟!110001沈阳 张春生!110001沈阳 |
| 作者单位： | 中国医科大学附属一院 |
| 摘 要： | 采用动物肿瘤模型实验方法探讨葡萄糖酸锗对肿瘤的放射增敏效应。结果显示 :治疗后单药组与对照组肿瘤平均体积比较无显著差异 (P>0 .0 5 ) ,用药加放射 2 0 ,2 5 Gy组肿瘤平均体积分别明显小于单放 2 0 ,2 5 Gy组 (P<0 .0 1) ,当肿瘤体积达到 4 .4 cm3 时 (原照射体积的 4倍 )测得放射增敏比为 1.5 8～ 1.7。说明本药具有放射增敏作用 ,并能使肿瘤放射敏感性提高 5 8%～ 70 %。 |
| 关 键 词： | 葡萄糖酸锗 放射增敏 放射增敏剂 |
THE EXPERIMENT STUDY OF THE RADIOSENSITIVE EFFECT OF THE GERMANIUM GLUCONATE ON THE MOUSE WITH LEWIS LUNG CANCER |
|
| Chen Yanzhi,Wu Rong,Zhang Yinjuan,et al.. THE EXPERIMENT STUDY OF THE RADIOSENSITIVE EFFECT OF THE GERMANIUM GLUCONATE ON THE MOUSE WITH LEWIS LUNG CANCER[J]. Chinese Journal of Radiation Oncology, 1995, 0(4) | |
| Authors: | Chen Yanzhi Wu Rong Zhang Yinjuan et al. |
| Affiliation: | Chen Yanzhi,Wu Rong,Zhang Yinjuan,et al. China Medical University,Shen Yang,110001 |
| Abstract: | To research the radiosensitive effect of the germanium gluconate on the tumor, the animal tumor model was used in this paper. The results showed that after treatment,there was no difference of tumor average volume(TAV) between the drug alone and the control group (P>0.05);the TAV of the drug plus radiation dose of 20,25Gy groups were much smaller than that of the radiation alone groups (P<0.01);when the tumor volume reached 4.4 cm 3 (4 times the size of the original tumor volume), sensitivity enhance rate(SER) were 1.58 to 1.7. This means that this drug may increase the radiosensitivity from 58% to 70%. |
| Keywords: | Germanium gluconate Radiosensitive |
| 本文献已被 CNKI 等数据库收录！ | |