^99mTc—DTPA肾动态显像在先天性肾发育不良诊断中的临床应用

目的：探讨^99mTc-二乙三氨五醋酸（DTPA）肾动态显像在先天性肾发育不良诊断中的临床应用价值。方法：12例先天性肾发育不良患者均行^99mTc-DTPA肾动态显像和腹部超声检查，其中11例行腹部增强CT扫描，8例行静脉肾盂造影（IVP）。结果：^99mTc-DTPA肾动态显像发现肾发育不良7例（58.3％，7／12），探测灵敏度与增强CT相当（X^2=1．5，P〉0．05），优于B超（X^2=4．4，P〈0．05）；8例行IVP检查者仅发现肾发育不良2例。患侧肾小球滤过率（GFR）明显低于健侧（t=10．2，P〈0．05）。结论99mTc-DTPA肾动态显像是一种能有效诊断肾发育不良、并同时评价肾功能的无创性影像手段。

Clinical application of 99mTc-DTPA renal dynamic imaging in the diagnosis of patients with congenital renal dysplasia

Objective： To discuss the clinical application value of renal dynamic imaging in the diagnosis of patients with congenital renal dysplasia. Methods： Twelve cases with congenital renal dysplasia underwent ^99mTc-DTPA renal dynamic imaging and abdominal ultrasound examination, 11 cases among them underwent abdominal enhanced CT scan, and 8 cases among them underwent intravenous pyelography （IVP）. Results： Seven cases were diagnosed by ^99mTc-DTPA renal dynamic imaging （58.3%, 7/12）. The detection sensitivity by DTPA imaging was equivalent to enhanced CT scan（X^2=1.5, P〉0.05）, and was superior to ultrasound （X^2=4.4, P〈0.05）. Only 2 cases among 8 cases underwent IVP. The average values of GFR in the affected side kidney were obviously lower than normal side kidney（t=10.2, P〈0.05）. Conclusions： ^99mTc-DTPA renal dynamic imaging is an effective tool to diagnose renal dysplasia and evaluate kidney function at the same time.