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Progress of Studies on Traditional Chinese Medicine Based onComplex Network Analysis
Affiliation:a.Specialty Committee on Network Pharmacology, World Federation of Chinese Medicine Societies, Beijing 100084,bState b.Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences,University of Macau, Macau 999078, China,a.Specialty Committee on Network Pharmacology, World Federation of Chinese Medicine Societies, Beijing 100084,bState b.Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences,University of Macau, Macau 999078, China,a.Specialty Committee on Network Pharmacology, World Federation of Chinese Medicine Societies, Beijing 100084, c.Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700 and a.Specialty Committee on Network Pharmacology, World Federation of Chinese Medicine Societies, Beijing 100084,bState b.Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences,University of Macau, Macau 999078, China
Abstract:Traditional Chinese medicine(TCM) is a distinct medical system that deals with the life-health-disease-environment relationship using holistic, dynamic, and dialectical thinking. However, reductionism has often restricted the conventional studies on TCM, and these studies did not investigate the central concepts of TCM theory about the multiple relationships among life, health, disease, and environment. Complex network analysis describes a wide variety of complex systems in the real world, and it has the potential to bridge the gap between TCM and modern science owing to the holism of TCM theory. This article summarizes the current research involving TCM network analysis and highlights the computational tools and analysis methods involved in this research. Finally, to inspire a new approach, the article discussed the potential problems underlying the application of TCM network analysis.
Keywords:Complex network analysis   formula   mechanism   syndrome   traditional Chinese medicine
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