皮肤结节性红斑63例临床病理特征分析

目的探讨皮肤结节性红斑的临床和病理特征及其鉴别诊断要点。方法回顾分析63例结节性红斑的组织病理切片。结果结节性红斑多见于中青年女性，好发于小腿，以红色结节为主要皮疹，病理表现为内皮细胞增生，血管壁增厚，管腔变窄，不同程度的间隔性脂膜炎，同时有表皮均匀肥厚的病理改变。结论表皮均匀肥厚也可作为结节性红斑病理诊断的一条线索。

To study the clinical and pathological characteristics of cutaneous erythema nodosum

Objective To study the clinical and pathological and differential diagnosis characteristics of cutaneous erythema nodosum. Methods The pathological slices of 63 erythema nodosum eases were analyzed retrospectively. Results Erythema nodosum desease was frequendy suffered by middle-young females,and the lesions showed mainly bright red color nodules and were usually located on the anterior aspects of the legs. Histopathologically,it had been concluded as a main histopathologic hallmark of erythema nodosum that showed the hyperplastic vascular endothclium,thicked wall and stenosis of blood vessels cavity, slight or moderate septal panniculitis with no vasculitis, and the epidermal was uniform hyperplasia. Conclusion Epidermal uniform hyperplasia which has not been given our attention in the study previously can also serve as a clue to help patholygic diagnose in cutaneous erythema nodosum.