A case of sarcomatoid carcinoma of the thymus |
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Authors: | Mitsuyo Nishimura Tetsuro Kodama Hiroyuki Nishiyama Yutaka Nishiwaki Tomoyuki Yokose Yukio Shimosato |
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Affiliation: | Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa;Pathology Division, National Cancer Center Research Institute East, Kashiwa;Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan;Department of Surgery, The Social Health Insurance Medical Center, Tokyo |
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Abstract: | A 57-year-old woman presented with a 10×10 cm anterior mediations mass. The tumor had Invaded the pericardium, both lungs and the left brachiocephallc vein, and was treated by partial resection and postoperative radiation therapy. Pathological examination of the tumor revealed squamous cell carcinoma with a spindle cell sarcomatous component. Immunohistochemically, keratin and epithelial membrane antlgen were posltive In both the spindle cell sarcomatous areas and the squamous cell carcinomatous area and thus, a diagnosis of thymic carcinoma of sarcomatoid type was made. The patient died of recurrent disease 1 year after surgery. This case is the seventh reported In the English literature Because of the poor outcome, adjuvant therapy is recommended. |
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Keywords: | keratin sarcomatoid carcinoma squamous cell carcinoma thymic carcinoma thymus |
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