Turcot综合征的内镜特点

目的 探讨Turcot综合征的内镜特点及遗传特性。方法 回顾1976-2004年所有结肠镜检查的患者，符合Turcot综合征定义的共有2例，结合文献，探讨该综合征的特点。结果 家族性腺瘤样息肉病型1例为男性，55岁，遗传性非腺瘤病结直肠癌型（lynch综合征）1例，为女性，58岁。两者均以结肠病变为首发症状，都死于脑部胶质细胞瘤。结论 Turcot综合征为少见遗传病，对其加强监测，可早期诊断及时治疗，改善愈后。

Endoscopic characteristics of Turcot syndrome

[Objective] To discuss the endoscopic characteristics and hereditary of Turcot syndrome. [Method] We reviewed the patients who have been done colonoscopy from 1976 to 2004. Two cases of Turcot syndrome were found and the characteristic of the syndrome was discussed combined with 1iterature. [Result] One case suffered from familiar adenomatous polyposis, who is male and 55yrs old;The other is hereditary nonpolyposis colorectal cancer(Lynch syndrome),who is female and 58yrs old. Colonic change was showed first in both patients,and the cause to death for them is same: Glioblatoma in brain. [Conclusion] Turcot syndrome is a rare hereditary disease. If monitored carefully, it can be dignosed and treated in time.