电针刺在内毒素休克中的防治作用

背景内毒素休克是临床上常见的急危重症之一，常使原发病病情复杂化和严重化，因其来势凶猛、进展迅速以及病死率高，一直倍受医学界广泛关注。目的阐述电针刺在内毒素休克中的防治作用。内容针刺可通过抑制肿瘤坏死因子（tumor necrosis factor，TNF）啾、白细胞介素（interleukin，IL）-6、一氧化氮（nitricoxide，NO）和氧自由基等对内毒素休克有改善微循环、纠正血压、调整体液因素及保护重要脏器等作用。趋向内毒素休克的发病机制很复杂，电针刺能调动内源性保护系统，可能通过对相关信号转导通路的影响，应用于临床上内毒素休克及重要器官损伤的防治。

Therapeutic effect of electro-acupuncture in endotoxic shock

Background Endotoxic shock is one of clinical devastating symptom in common, which lead to the protopathy more serious and complexed. It has been paid more attention in the field of medicine because of its feral, rapid progress and high mortality. Objective This review summarized the therapeutic effect of electro-acupuncture in endotoxic shock. Content Electro- acupuncture plays an important role in stabling microcirculation, improving blood pressure, adjusting humoral factors and protecting important organs in endotoxic shock by inhibiting tumor necrosis factor （TNF）-α, interleukin （IL）-6, nitric oxide （NO） and oxygen free radical and so on. Trend The pathogenesis of endotoxic shock is complicated, and electro-acupuncture may be applied to remedy endotoxic shock and the damage of important organs by mobilizing endogenous protective system and the related signal transduction pathways.