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| 常州地区单采血小板献血者抗丙型肝炎病毒抗体阳性的调查及丙型肝炎病毒-RNA含量的临床研究 | |
| 引用本文： | 闵志军,张力超,张建伟,何亚琴,徐培君,王永忠. 常州地区单采血小板献血者抗丙型肝炎病毒抗体阳性的调查及丙型肝炎病毒-RNA含量的临床研究[J]. 实用医技杂志, 2010, 17(1): 9-11 |
| 作者姓名： | 闵志军 张力超 张建伟 何亚琴 徐培君 王永忠 |
| 作者单位： | 1. 常州市中心血站 2. 苏州大学医学院,215007 3. 江苏省常州市中心血站 4. 江苏省常州市三院肝病研究所 |
| 基金项目： | 江苏省常州市卫生局资助(wj200447) |
| 摘 要： | 目的调查常州地区单采血小板献血者抗丙型肝炎病毒(HCV)抗体的阳性率,探讨单试剂检测和双试剂检测对抗HCV抗体阳性检出率的差异。方法应用酶联免疫吸附试验(ELISA)法检测单采血小板献血者血清中的抗HCV抗体,对抗HCV抗体的阳性献血者,应用荧光定量聚合酶链反应(FQ-PCR)技术检测其血清HCV-RNA含量。结果本地区单采血小板献血者抗HCV抗体阳性率低于外来人员(χ2=23.59,P<0.01)。单试剂检测抗HCV抗体阳性献血者的HCV-RNA阳性率低于双试剂检测组(χ2=14.09,P<0.01),单试剂检测组的HCV-RNA含量也低于双试剂检测组(t=5.29,P<0.01)。结论在没有核酸检测的条件下,对血小板献血者抗HCV抗体进行双试剂检测很有必要。 |
| 关 键 词： | 肝炎抗体,丙型 单采血小板献血者 肝炎病毒-RNA |
Investigation of the rate of anti-hepatitis C virus antibody in platelet donors and clinical study of serum HCV-RNA in anti-HCV positive platelet donors |
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| MIN Zhi-jun,ZHANG Li-chao,ZHANG Jian-wei,HE Ya-qin,XU Pei-jun,WANG Yong-zhong. Investigation of the rate of anti-hepatitis C virus antibody in platelet donors and clinical study of serum HCV-RNA in anti-HCV positive platelet donors[J]. Journal of Practical Medical Techniques, 2010, 17(1): 9-11 | |
| Authors: | MIN Zhi-jun ZHANG Li-chao ZHANG Jian-wei HE Ya-qin XU Pei-jun WANG Yong-zhong |
| Abstract: | Objective To investigate the rate of anti-hepatitis C virus(HCV) in platelet donors in Changzhou area,and to explore the difference of the HCV-RNA positive detection rate between the single reagent detecting group and double reagent detecting group. Methods The anti-HCV antibody was measured by ELISA assay,and the content of serum HCV-RNA of the anti-HCV antibody positive platelet donors was detected by FQ-PCR assay. Results The rate of anti-HCV antibody in local platelet donors was lower than that of migra... |
| Keywords: | Hepatitis C antibodies Platelet donors Hepacivirus-RNA |
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