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Histological changes at an endosonography-guided biliary drainage site: A case report
作者姓名:Fujita N  Noda Y  Kobayashi G  Ito K  Obana T  Horaguchi J  Takasawa O  Nakahara K
作者单位:Department of Gastroenterology Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan,Department of Gastroenterology,Sendai City Medical Center,Sendai,Japan
摘    要:Endosonography-guided biliary drainage (ESBD) is a new method enabling internal drainage of an obstructed bile duct. However, the histological conditions associated with fistula development via the duodenum to the bile duct have not been reported. We performed ESBD 14 d preoperatively in a patient with an ampullary carcinoma and histologically confirmed changes in and around the fistula. The female patient developed no complications relevant to ESBD. Levels of serum bilirubin and hepatobiliary enzymes declined quickly, and pancreatoduodenectomy was carried out uneventfully. The resected specimen was sliced and stained with hematoxylin-eosin. Histological evaluation of the puncture site in the duodenum and bile-duct wall, and the sinus tract revealed no hematoma, bile leakage, or abscess in or around the sinus tract. Little sign of granulation, fibrosis, and inflammatory cell infiltration was observed. Although further large-scale confirmatory studies are needed, the findings here may encourage more active use of ESBD as a substitute for percutaneous transhepatic drainage in cases with failed/difficult endoscopic biliary stenting.

关 键 词:内窥镜检查  内镜胆管引流  黄疸  胆汁
收稿时间:2007 May 20

Histological changes at an endosonography-guided biliary drainage site: a case report
Fujita N,Noda Y,Kobayashi G,Ito K,Obana T,Horaguchi J,Takasawa O,Nakahara K.Histological changes at an endosonography-guided biliary drainage site: a case report[J].World Journal of Gastroenterology,2007,13(41):5512-5515.
Authors:Fujita Naotaka  Noda Yutaka  Kobayashi Go  Ito Kei  Obana Takashi  Horaguchi Jun  Takasawa Osamu  Nakahara Kazunari
Institution:Department of Gastroenterology, Sendai City Medical Center, Sendai, Japan
Abstract:Endosonography-guided biliary drainage (ESBD) is a new method enabling internal drainage of an obstructed bile duct. However,the histological conditions associated with fistula development via the duodenum to the bile duct have not been reported. We performed ESBD 14 d preoperatively in a patient with an ampullary carcinoma and histologically confirmed changes in and around the fistula. The female patient developed no complications relevant to ESBD. Levels of serum bilirubin and hepatobiliary enzymes declined quickly,and pancreatoduodenectomy was carried out uneventfully. The resected specimen was sliced and stained with hematoxylin-eosin. Histological evaluation of the puncture site in the duodenum and bile-duct wall,and the sinus tract revealed no hematoma,bile leakage,or abscess in or around the sinus tract. Little sign of granulation,fibrosis,and inflammatory cell infiltration was observed. Although further large-scale confirmatory studies are needed,the findings here may encourage more active use of ESBD as a substitute for percutaneous transhepatic drainage in cases with failed/difficult endoscopic biliary stenting.
Keywords:Endosonography  Endoscopic ultrasound-guided fine needle aspiration  Endoscopic biliary drainage  Biliary scenting  Endoscopic retrograde cholang iopancreatography  Obstructive jaundice  Biliary stricture
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