2006-2011年我院铜绿假单胞菌分布及耐药性分析

目的了解2006-2011年我院铜绿假单胞菌临床分布及耐药性,为临床合理选用抗菌药物提供依据。方法对我院各类临床标本分离出的铜绿假单胞菌的检出率、分布特点及药敏结果进行回顾性分析。结果铜绿假单胞菌在痰标本中检出率最高,其次是尿液标本,平均检出率分别为81.5%和8.3%;铜绿假单胞菌对多粘菌素B敏感性最好,耐药率最低,其次是头孢哌酮/舒巴坦。结论铜绿假单胞菌感染以上呼吸道为主,可引起多部位感染,其耐药性高,应规范临床用药,加强铜绿假单胞菌耐药性监测,有效控制感染。

Distribution of pseudomonas aeruginosa in our hospital from 2006-2011 and its drug resistance

Objective To provide the evidence for the rational use of antibiotics by investigating the distribution pseudomonas aeruginosa in our hospital from 2006 to 2011 and its drug resistance.Methods The detection rate,distribution characteristics and drug sensitivity test findings of pseudomonas aeruginosa isolated from a variety of clinical specimens were retrospectively analyzed.Results The detection rate of pseudomonas aeruginosa in sputum samples was the highest followed by in urine specimens,with a detection rate of 81.5% and 8.3%,respectively.The pseudomonas aeruginosa was most sensitive and resistant to polymyxin B followed by cefoperazone and sulbactam.Conclusion Highly drug resistant pseudomonas aeruginosa can cause infection in many other sites,especially in the upper respiratory tract.Antibiotics should be rationally used for pseudomonas aeruginosa infection and drug resistance of pseudomonas aeruginosa should be closely monitored in order to effectively control its infection.