Larvicidal,antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region,Tanzania |
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| Authors: | Ramadhani S O Nondo Zakaria H Mbwambo Abdul W Kidukuli Ester M Innocent Matobola J Mihale Paul Erasto Mainen J Moshi |
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| Affiliation: | (1) Department of Biological and Pre-Clinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences (MUHAS), P.O. Box 65001, Dar es Salaam, Tanzania;(2) Department of Natural Products Development and Formulation, Institute of Traditional Medicine, MUHAS, P.O.BOX 65001, Dar es Salaam, Tanzania;(3) Department of Physical Sciences, Open University of Tanzania, P.O. Box 31608, Dar es Salaam, Tanzania |
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| Abstract: | Background The leaves and roots of Cissampelos mucronata A. Rich (Menispermaceae) are widely used in the tropics and subtropics to manage various ailments such as gastro-intestinal complaints, menstrual problems, venereal diseases and malaria. In the Coast region, Tanzania, roots are used to treat wounds due to extraction of jigger. Leaves of Tephrosia villosa (L) Pers (Leguminosae) are reported to be used in the treatment of diabetes mellitus in India. In this study, extracts from the roots and aerial parts of C. mucronata and extracts from leaves, fruits, twigs and roots of T. villosa were evaluated for larvicidal activity, brine shrimps toxicity and antimicrobial activity. |
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