川崎病68例临床分析

目的探讨川崎病（KD）的诊断及临床表现特点。方法对我科近6年（2004年1月至2009年12月）住院的68例KD患儿的临床资料进行回顾性分析及总结。结果 KD近3年（2007年1月至2009年12月）的患儿人数是前3年（2004年1月至2006年12月）患儿人数的1.72倍（43/25）,68例中男女比例为1.96：1（45/23）,5岁以下患儿发病占94.1%（64/68）,非典型KD占32.4%（22/68）。典型KD组和非典型KD组在性别、年龄、实验室检查及心脏冠状动脉损害方面比较差异无统计学意义（P〉0.05）;典型KD组与非典型KD组在皮疹、结膜充血、淋巴结肿大、脱屑与硬肿方面比较差异有统计学意义（P〈0.05）。结论 KD发病中非典型表现发生率有逐渐增加趋势,容易误诊,尽早做心脏彩色多普勒检查对诊断KD有重要意义。

Clinical Analysis of 68 Children with Kawasaki disease

Objective To analyze the diagnosis and clinical characteristics of Kawasaki disease（KD）.Methods Clinical data of 68 children with KD were retrospectively analyzed and summarized.Results The number of children with KD was 43 in recent 3 years（2007.01-2009.12）,while the number of children with KD was 25 3 years earlier（2004.01-2006.12）.A male predominance was apparent（1.96：1） in 68 children with KD.94.1% cases occurred in children under 5 years old,and 32.4% cases were atypical.Significant difference was found in rash,conjunctival congestion,lymphadenectasis,desquamation and swelling of the extremities between typical and atypical KD（P 0.05）,but not in sex,age,laboratory tests and coronary artery damage.Conclusion Incidence rate of atypical KD increases gradually,and the color Doppler examination of heart is of great help to diagnose KD.