北京地区部分人群接触密切的家畜(禽)戊型肝炎病毒感染血清学调查

目的 了解北京地区戊型肝炎(戊肝)病毒感染现状.方法 采用EIA诊断试剂检测人群、猪和鸡血清中戊肝病毒(HEV)抗体.结果 1208份人群血清中有260份HEV-IgG抗体阳性,总阳性率为21.52%,对260份HEV IgG阳性血进行IgM抗体检测,有22份阳性,占8.46%.32份猪血清中有15份阳性,阳性率为46.88%,34份鸡血清HEV抗体全部为阴性.人群不同年龄组HEV抗体阳性率依次为11～20岁为5.60%(14/250),21～30岁为20%(42/210),31～40岁为24.03%(62/258),41～50岁为26.44%(78/295),51～60岁为32.82%(64/195),男女不同性别HEV感染率比较,男性阳性率为29.51%(144/488),女性为21.70%(102/470).结论 北京地区人群和与人接触密切的家畜猪均存在戊肝病毒感染,人群戊肝病毒感染率随年龄增长而升高,尤其是男性戊肝病毒感染率明显高于女性,郊区流动人群戊肝病毒感染率明显高于市内人群,家畜猪感染率是人群的2倍以上.

Antibody detection of hepatitis E virus in some human population, swine and chicken in Beijing in China

Objective To investigate the seroprevalence of HEV infection in human population, swine and chicken in Beijing region. Methods EIA was used for detecting anti-HEV IgG of the serum samples. All samples were collected in 2006-2007 in Beijing areas. Results The anti-HEV IgG was detected positive in 21.52% of human(260/1208), 46.88 % (15/32)of swine, but was negative in chickens (0/24). The positive rate of human at different age group, was 5.60% (14/250)of 11-20 year, 20% (42/210)of 21-30 year,24.03% (62/258)of 31-40 year, 26.44% (78/295)of 41-50 year, 32.82% (64/195)of 51-60 year. The male(29.51% ) was higher than the female (21.70%). Conclusion The HEV infection was correlation with age and sex significandy. The infection rate was increased with age, the positive rate in swine was more double than the human population.