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| 氯沙坦与福辛普利、卡托普利对老年高血压患者尿白蛋白排泄量和内生肌酐清除率的对比研究 | |
| 引用本文： | 季洪赞,杨俊中,乔小云. 氯沙坦与福辛普利、卡托普利对老年高血压患者尿白蛋白排泄量和内生肌酐清除率的对比研究[J]. 中国循环杂志, 2001, 16(1): 36-37 |
| 作者姓名： | 季洪赞 杨俊中 乔小云 |
| 作者单位： | 1. 中国人民解放军南京军区南京总医院南京军区老年病研究中心老年病二科 2. 中国人民解放军南京军区南京总医院南京军区老年病研究中心老年病一科 3. 中国人民解放军南京军区南京总医院南京军区老年病研究中心药剂科 |
| 摘 要： | 目的观察氯沙坦和血管紧张素转换酶抑制剂对老年原发性高血压患者尿白蛋白排泄量(UAER)与内生肌酐清除率(Cr-C)的影响,比较不同作用途径血管紧张素拮抗剂类药物上述作用的差别。方法选择162例老年2～3级原发性高血压患者,UAER在453±39mg/24h,Cr-C在50.0±19.2ml/min |
| 关 键 词： | 氯沙坦福辛普利卡托普利老年人高血压 |
| 文章编号： | 1000-3614(2001)01-0036-02 |
| 修稿时间： | 2000-08-28 |
A Comparison between theEffects of Losartan and Fosinopril,Captopril on the Excretion Rate of Urinary Albumin andthe Clearance of Endogenous Creatinine in Elderly Hypertensive Patients |
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| Ji Hongzan,Yang Junzhong,Qiao Xiaoyun. A Comparison between theEffects of Losartan and Fosinopril,Captopril on the Excretion Rate of Urinary Albumin andthe Clearance of Endogenous Creatinine in Elderly Hypertensive Patients[J]. Chinese Circulation Journal, 2001, 16(1): 36-37 | |
| Authors: | Ji Hongzan Yang Junzhong Qiao Xiaoyun |
| Abstract: | Objective:To evaluate the effects of losartan、fosinopril and captopril on the excretion rate of urinary albumin (UAER) and the clearance of endogenous creatinine (Cr-C) in elderly patients. Methods:In this study,162 elderly patients with stage of the 2—3 class hypertension were included,The patients were divided into 3 groups,that were losartan group and the fosinopril group and captopril group,the anti-hypertensive effects and UAER and Cr-C were determined before and after the treatment. Results:The hypertensive effect rates were 94% in losartan group and 93%、93% in fosinopril group and captopril group respectively.Decrease of UAER was observed in 89% of patient in losartan group and 59%、50% in fosinopril group、captopril group.Cr-C were improved in 94%、78% of patient in losartan group and in fosinopril group and 63% in captopril group. Conclusions:Losartan has better effects on UAER and Cr-C than captopril in elderly hypertensive patients. |
| Keywords: | Losartan Fosinopril Captopril The elderly Hypertension |
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