| 消化性溃疡患者血清LPO含量及SOD活性变化的初步研究 |
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| 引用本文： | 陈建中,陈建华.消化性溃疡患者血清LPO含量及SOD活性变化的初步研究[J].贵州医药,1996,20(6):323-324. |
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| 作者姓名： | 陈建中 陈建华 |
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| 作者单位： | 黔南州人民医院 |
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| 摘 要： | 对８４例消化性溃疡患者血清ＬＰＯ含量及Ｃｕ，Ｚｎ－ＳＯＤ活性进行了测定，发现胃溃疡及复合性溃疡患者血清ＬＰＯ含明明显高于正常对照（Ｐ〈０．００１），血清Ｃｕ，Ｚｎ－ＳＯＤ活性则显低于正常对照（Ｐ〈０．０１）；十二指肠球部溃疡患者血清ＬＰＯ含量有升高趋势，而血清Ｃｕ，Ｚｎ－ＳＯＤ活性在正常范围，结果提示，胃溃疡的发生可能与氧自由基的作用有关。
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| 关 键 词： | 消化性溃疡 脂质过氧化酶 超氧化物歧化酶 |
PRELIMINARY STUDY OF SERUM LIPID PEROXIDES CONTENT AND SUPEROXIDE DISMUTASE ACTIVITIES IN PATIENTS WITH PEPTIC ULCER |
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| Chen Jianzhong,et al..PRELIMINARY STUDY OF SERUM LIPID PEROXIDES CONTENT AND SUPEROXIDE DISMUTASE ACTIVITIES IN PATIENTS WITH PEPTIC ULCER[J].Guizhou Medical Journal,1996,20(6):323-324. |
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| Authors: | Chen Jianzhong |
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| Institution: | Chen Jianzhong, et al. |
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| Abstract: | Serum lipid peroxides (LPO) contents and Cu, Zn-superoxide dismutase (Cu, Zn-SOD) were measured in 84 patients with peptic ulcer. The result showed that serum LPO content was stenificantly higher in patients with gastric ulcer and composite ulcet than normal subjects (P <0. 001), while serum Cu. Zn-SOD activities decreased markedly as compared with the mormal (P <0. 01 ). The serum LPO content of the patients with duodend ulcer was slightly higher than narmal subjects, but serum Cu, Zn-SOD activities remained normal. It suggested that oxygen free radicals may play a role in formation of gastric ulcer. |
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| Keywords: | Peptic ulcer lipid peroxides Cu Zn-Superoxide dismutase Oxygen free radicals |
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