Use of zinc metallothioneine to protect mice from ionizing radiation |
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Authors: | A N Koterov Z A Trebenok I V Filippovich |
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Institution: | (1) Institute of Biophysics, Ministry of Health of the Russian Federation, Moscow |
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Abstract: | Injecting mice with exogenous zinc-metallothioneine from rat liver at 2 mg/kg 5–10 min before their total-body irradiation
resulted in a significantly increased 30-day survival rate. The radioprotective effect of zinc-metallothioneine was not associated
with the influence of its constituents, since a model mixture composed of these (albumin, cysteine, and zinc) failed to protect.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
o
8, pp. 139–141, August, 1994
Presented by B. B. Moroz, Member of the Russian Academy of Medical Sciences |
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Keywords: | zinc metallothioneine mice protection ionizing radiation |
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