慢性前列腺炎患者病原菌检出分布及其耐药性

目的了解慢性前列腺炎患者病原菌分布情况及其耐药性。方法用Mears2Stamey四杯法采集患者的前列腺液进行细菌培养和药敏试验。结果208例慢性前列腺炎患者中115例分离出细菌119株，阳性率为55．3％，4例为混合感染。细菌种类有14种，其中革兰阳性菌占82．4％，以凝固酶阴性葡萄球菌（CNS）为主占52．9％；革兰阴性菌占17．6％，以大肠埃希菌占优势（10．9％）。细菌对临床常用抗菌药物的耐药率普遍较高，葡萄球菌属中耐苯唑西林凝固酶阴性葡萄球菌（MRSCN）高这77．8％，对万古霉素、克林霉素、左旋氧氟沙星和复方新诺明的敏感性较好；大肠杆菌仅对亚胺培南和阿米卡星显示较好的敏感性。结论及时了解慢性前列腺炎患者病原菌的分布厦其耐药性，对诊断和治疗慢性前列腺炎具有重要的意义。

The distribution of pathogenic bacteria detected from chronic prostatitis patients and analysis of drug resistance

Objective To understand the distribution and resistance of pathogens isolated from chronic prostatitis patients. Methods The prostatic fluid of patients collected bymears2stamey methods was cultured and resistance screen test was carried out. Results There were 119 bacterium strains were isolated from 115 cases. The sensitivity was 55.3% and 4 cases were mixed infections. The 119 bacterium strains belonged to 14 different species. The gram positive bacreria were accounted for 82.4 % of which the coagulase negative Staphylococcus was accounted for 52.9%. The gram negative bacteria were 17.6% of which the Escherichia coli was accounted for 10.9%. The resistance rate of the baciteria to the clinical antibacterial agents was high, 77.8% of MRSCN staphylococcus was resistant to antibiotics. But the baciteria were sensitive to the vancomycin, clindamycin, Levifloxacin and Trinethoprim/sulfamethoxazole. Escherichia coli was sensitive only to Imipenem and Amikacin. Conclusion It was very important to know the distribution and resistance of pathogens isolated from chronic prostatitis in time for clinical diagnosis and treatment.