| 持续滴注诺维本联合异环磷酰胺治疗铂类耐药的非小细胞肺癌的临床研究 |
| |
| 引用本文： | 潘战宇,闫祝辰,谢广茹,王毓敏,乔卉. 持续滴注诺维本联合异环磷酰胺治疗铂类耐药的非小细胞肺癌的临床研究[J]. 中国肿瘤临床, 2001, 28(5): 361-364 |
| |
| 作者姓名： | 潘战宇 闫祝辰 谢广茹 王毓敏 乔卉 |
| |
| 作者单位： | 天津医科大学附属肿瘤医院中西医结合科, |
| |
| 摘 要： | 目的：临床研究持续性静脉滴注诺维本（Navelbine,NVB)联合异环磷酰胺（Ifosfamide,IFO)治疗铂类耐药的非小细胞肺癌（NSCLC）的疗效与毒副反应。方法：入组非小细胞肺癌27例，临床予持续性静脉滴注NVB联合IFO化疗，至少两个疗程，疗效及毒性判定按照WHO标准，结果：有效率为18．5％，在毒副反应方面，表现不同程度的白细胞下降，血小板下降，结论：本项研究提示持续性静脉滴注NVB联合IFO方案治疗铂类耐药的非小细胞肺癌有较高疗效，并较为安全，患者可接受。
|
| 关 键 词： | 联合化疗 诺维本 持续性滴注 临床研究 非小细胞肺癌 异环磷酰胺 |
| 文章编号： | 1000-8179(2001)05-0361-04 |
| 修稿时间： | 2000-09-21 |
Continuous Intravenous Dripping of Navelbine Combined wity Ifosfamide InTreatment of Platinum-Resistant Non-small Cell Lung Cancer |
| |
| Pan Zhanyu Yan Zhuchen Xie Guangru et al. Continuous Intravenous Dripping of Navelbine Combined wity Ifosfamide InTreatment of Platinum-Resistant Non-small Cell Lung Cancer[J]. Chinese Journal of Clinical Oncology, 2001, 28(5): 361-364 |
| |
| Authors: | Pan Zhanyu Yan Zhuchen Xie Guangru et al |
| |
| Affiliation: | Pan Zhanyu Yan Zhuchen Xie Guangru et al Department of Combined Traditional Chinese and Western Medicine,Cancer Hospital Of Tianjin Medical University,Tianjin |
| |
| Abstract: | Objective: To evaluate the effect of continuous intravenous dripping of navelbine (NVB) combined with ifosfamide (IFO) in treatment of platinum agents resistant non-small cell lung cancer (NSCLC). Methods: Twenty-seven cases of NSCLC were treated with combination chemotherapy consisting of continuous dripping of NVB and IFO for at least two cycles. The therapeutic effects and toxicity were evaluated according to the WHO criteria. Results: The total response rate was 18.5% and the main side-effects were leukopenia in some extent and thrombocytopenia, and in some cases, nausea and vomiting were observed. Conclusion: The results of this study shows that continuous dripping of NVB combined with IFO has a safe and higher therapeutic effect on NSCLC. |
| |
| Keywords: | Combination chemotherapy Navelbine Continuous intravenous dripping Non-small cell lung cancer |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
