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子宫内膜异位症患者治疗前后血清TSGF和血浆VEGF水平的临床意义
引用本文:施绍红,田小平.子宫内膜异位症患者治疗前后血清TSGF和血浆VEGF水平的临床意义[J].放射免疫学杂志,2006,19(1):67-68.
作者姓名:施绍红  田小平
作者单位:江苏省连云港市第一人民医院妇产科,222002;江苏省连云港市第一人民医院妇产科,222002
摘    要:目的:探讨了子宫内膜异位症患者治疗前后血清TSGF和血浆VEGF水平的变化及临床意义。方法:应用ELISA法测定31例子宫内膜异位症患者血浆VEGF含量,光电比色法测定TSGF含量,并与30名正常健康人作比较。结果:子宫内膜异位症患者在治疗前血清TSGF和血浆VEGF水平非常显著地高于正常人组(P>0.01)。经中西医结合治疗后3个月,则与正常人组比较无显著性差异(P〉0.05)。结论:子宫内膜异位症的发生与发展与血清TSGF和血浆VEGF水平密切相关。

关 键 词:子宫内膜异位症  肿瘤特异性生长因子  血管内皮生长因子
收稿时间:2005-12-03
修稿时间:2005年12月3日

Clinical Significance of Determination of Changes of Serum TSGF and Plasma VEGF Levels After Treatment in Patients with Endometriosis
Shi Shaohong,Tian Xiaoping.Clinical Significance of Determination of Changes of Serum TSGF and Plasma VEGF Levels After Treatment in Patients with Endometriosis[J].Journal of Radioimmanology,2006,19(1):67-68.
Authors:Shi Shaohong  Tian Xiaoping
Abstract:Objective To investigate the changes of serum TSGF and plasma VEGF levels after treatment in patients with endometriosis.Methods Serum TSGF levels were determined with ELISA and plasma VEGF levels with biochemistry in 31patients with endometrosis both before and after treatment as well as in 30 controls.Results Before treatment the serum TSGF and plasma VEGF levels in patients were significantly higher than those in the controls(P<0.01).After three months of treatment with combined western and traditional Chinese medicine the levels dropped markedly and was not significantly different from those in controls(P>0.05).Conclusion Development of endometriosis were closely related to the plasma levels of VEGF and serum TSGF levels.
Keywords:endometriosis  tumor specific growth factors(TSGF)  vascular endothelial growth factor(VEGF)
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