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| ASC-US患者HPV-DNA分型检测的临床意义 | |
| 引用本文： | 李曼,姚军,钟萍,朱春江,曾思恩. ASC-US患者HPV-DNA分型检测的临床意义[J]. 中国妇幼保健, 2011, 26(11): 1691-1694 |
| 作者姓名： | 李曼 姚军 钟萍 朱春江 曾思恩 |
| 作者单位： | 1. 桂林医学院附属医院妇产科,广西,桂林,541001 2. 桂林医学院附属医院围产实验室 3. 桂林医学院附属医院病理实验中心 |
| 基金项目： | 广西壮族自治区自然科学基金资助项目 |
| 摘 要： | 目的:探讨ASC-US患者HPV-DNA分型检测的临床意义。方法:对2008年1月～2010年1月在桂林医学院附属医院妇产科同时行宫颈细胞学筛查以及HPV-DNA分型检测其中宫颈细胞学结果判读为ASC-US的138例患者的相关资料进行分析。结果:138例ASC-US患者中HPV-DNA分型检测高危亚型阳性者61例,占44.20%,其中HPV-DNA16或(和)58亚型阳性者46例,占总数的33.33%,占高危阳性的75.41%。HPV-DNA高危亚型阳性对CINⅡ及以上病变检出的敏感度为91.67%,特异度为60.32%,对CINⅡ及以上者的阴性预测值为98.70%。HPV-DNA16/58亚型阳性对CINⅡ及以上病变检出的敏感度为58.33%,特异度为69.05%。结论:HPV-DNA分型检测在ASC-US患者分层处理中有意义,对HPV-DNA分型检测高危阳性患者需行阴道镜检查,其余可用宫颈细胞学随诊。 |
| 关 键 词： | ASC-US 人乳头状瘤病毒 宫颈上皮内瘤样病变 |
Clinical significance of HPV-DNA genotype detection in patients with ASC-US |
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| LI Man,YAO Jun,ZHONG Ping et al. Clinical significance of HPV-DNA genotype detection in patients with ASC-US[J]. Maternal and Child Health Care of China, 2011, 26(11): 1691-1694 | |
| Authors: | LI Man YAO Jun ZHONG Ping et al |
| Affiliation: | LI Man,YAO Jun,ZHONG Ping et al.Department of Gynecology and Obstetrics,Affiliated Hospital of Guilin Medical College,Guilin 541001,Guangxi,China |
| Abstract: | Objective:To explore the clinical significance of HPV-DNA genotype detection in patients with atypical squamous cells of undetermined significance(ASC-US). Methods:From January 2008 and January 2010,138 cases received cervical cytological screening and HPV-DNA genotype detection in the hospital,and their cervical cytological result was ASC-US,the related data of 138 cases were analyzed. Results:Among 138 cases with ASC-US,61 cases were found with positive high risk subtype of HPV-DNA,accounting for 44.20%,4... |
| Keywords: | Atypical squamous cells of undetermined significance Human papillomavirus Cervical intraepithelial neoplasm |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |