62例男性狼疮性肾炎临床分析

为提高对男性狼疮肾炎（ＭＬＮ）和女性狼疮肾炎（ＦＬＮ）差异的认识,减少临床误诊,本组对６２例ＭＬＮ与６２例随机选择的ＦＬＮ的临床表现、实验室检查、病理、疗效及预后进行了回顾性分析。结果显示ＭＬＮ和ＦＬＮ的发病年龄分布不同,ＳＬＥ中ＭＬＮ发生率高（Ｐ〈０．０５）,较易误诊（Ｐ〈０．０５）和延迟诊断（Ｐ〈０．０５）,且关节痛较ＦＬＮ少见,抗核抗体阳性率亦明显低于ＦＬＮ（Ｐ〈０．０１）,其他各项免疫指标

A clinic analysis of 62 male patients with lupus nephritis

To study the difference between male and female patients with lupus nephritis(LN),we made a retrospective analysis.The clinical characteristics of 62 male patients with LN were compared with 62 female patients with LN.The result indicated the distribution of LN onset ages was different between male and female patients with LN.The incidence of LN was higher in the male than in female patients with SLE.Male patients were often misdiagnosed or diagnosed long after the onset of the disease.Arthritis and positive rate of ANA were less commonly occurred in female patients with LN.Other clinical and pathologic features of LN were similar in male and female patients.The response to treatment and prognosis of male patients with LN was relatively poor.So male patients with LN should be paid more attention to.