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Successful Management of Chronic Refractory Immune Thrombocytopenia with Laparoscopic Splenectomy in a Patient with Acute Promyelocytic Leukemia |
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| Authors: | Ahmet Emre Eskazan Ayse Salihoglu Emine Gulturk Seniz Ongoren Aydin Nukhet Tuzuner Yildiz Aydin |
| Affiliation: | 1. Department of Hematology, Diyarbakir Training and Research Hospital, Diyarbakir, Turkey 2. Division of Hematology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey 3. Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey |
| Abstract: | Acute promyelocytic leukemia (APL) is a particular type of acute myeloid leukemia with characteristic biological and clinical features, the frequent association at diagnosis of a severe hemorrhagic diathesis. Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet counts and an increased risk of bleeding. Here we present a patient with the diagnosis of APL who achieved and maintained a remission with an induction consisting of idarubicin and ATRA, and then developed corticosteroid refractory ITP which is successfully treated with laparoscopic splenectomy. |
| Keywords: | Immune thrombocytopenia ITP Splenectomy Acute promyelocytic leukemia APL |
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