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采用UV法与HPLC法对易降解药品含量测定的比较
引用本文:罗卓雅,邱彪.采用UV法与HPLC法对易降解药品含量测定的比较[J].广东药学院学报,1997,13(3):164-166.
作者姓名:罗卓雅  邱彪
作者单位:广东省药品检验所
摘    要:采用紫外分光光度法与高效液色谱法,对盐酸氟西汀胶囊在不同贮存期进行含量测定比较,阐明采用紫外分光光度法测定某些易降解药品含量时,制定的方法只适用于测定该药品降解前的含量,对含量在含量限度下限的产品则应采用HPLC法进行分离测定。

关 键 词:HPLC  盐酸氟西汀  胶囊  含量测定  UVi法  易降解药

Comparison of UV and HPLC in the Determination of Easy Degraded Medicine
Luo Zhuoya,Chen Yongxin,Qiu Biao.Comparison of UV and HPLC in the Determination of Easy Degraded Medicine[J].Academic Journal of Guangdong College of Pharmacy,1997,13(3):164-166.
Authors:Luo Zhuoya  Chen Yongxin  Qiu Biao
Abstract:A ultravioletspectrophotometry method for the determination of fluoxetine in fluoxetine HCl capsules was compaired with HPLC. Results indicate that an established ultravioletspectrophotometry method for some easy degraded medicine can only be used before the active ingredient degraded. When the content of the active ingredient approachs inferior limit,HPLC should be use instead.
Keywords:ultravioletspectrophotometry  HPLC  fluoxetine HCl capsules
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