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舒利通颗粒的镇痛抗炎作用研究
引用本文:凌云,江海身,张永林,田军.舒利通颗粒的镇痛抗炎作用研究[J].中国药房,2005,16(11):819-820.
作者姓名:凌云  江海身  张永林  田军
作者单位:解放军海军总医院,北京市,100037
摘    要:目的:研究舒利通颗粒的镇痛抗炎作用。方法:采用醋酸建立小鼠疼痛扭体模型;采用二甲苯致小鼠耳廓肿胀和大鼠棉球肉芽肿形成模型;分别观察舒利通颗粒的镇痛及抗炎作用。结果:舒利通颗粒可显著降低小鼠扭体反应次数(P<0.01);减轻小鼠耳廓肿胀(P<0.05);减少大鼠肉芽肿形成(P<0.01)。结论:舒利通颗粒对疼痛和炎症具有明显的镇痛和抗炎作用。

关 键 词:舒利通颗粒  镇痛  抗炎
文章编号:1001-0408(2005)11-0819-02
修稿时间:2004年9月9日

Study on the Analgesic and Anti-inflammatory Effects of Shulitong Granule
LING Yun,JIANG Haishen,Zhang Yonglin,TIAN Jun.Study on the Analgesic and Anti-inflammatory Effects of Shulitong Granule[J].China Pharmacy,2005,16(11):819-820.
Authors:LING Yun  JIANG Haishen  Zhang Yonglin  TIAN Jun
Abstract:OBJECTIVE:To study the analgesic and anti-inflammatory effect of Shulitong granule.METHODS:The mice pain model was established by acetic acid;Dimethylbezene was used to make the external ears of the mice swollen and form cotton ball-shaped granuloma in rats so as to form models;The analgestic effect and anti-inflammatory effect of the Shulitong granule were observed respectively.RESULTS:Shulitong granule could reduce the writhing response times signifiˉcantly(P<0.01),alleviate the external ear swelling of the mice(P<0.05)and inhibit the formation of granuloma in rats(P<0.01).CONCLUSION:Shulitong granule has significant analgesic and anti-inflammatory therapeutic effects on pain and inf_ lammation.
Keywords:Shulitong granule  Analgesia  Anti-inflammation
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