脂肪母细胞瘤6例报告

目的探讨脂肪母细胞瘤的临床、病理及预后。方法对6例脂肪母细胞瘤临床资料、病理形态进行分析,并复习文献。结果6例中男4例,女2例。年龄5~32个月,平均14.5个月。发生于下肢2例,背部2例,上肢、右纵隔各1例。随访6个月~8年,平均随访期4年,复发率17%(1/6)。主要组织学特征为分叶状结构,可见原始间叶细胞、各种脂母细胞和成熟的脂肪细胞,丰富的毛细血管,伴不同程度的粘液样基质。结论脂肪母细胞瘤是一种少见的软组织良性肿瘤,可有局部复发,治疗方法主要为局部完整切除。需与粘液脂肪肉瘤鉴别。

The report of 6 cases with lipoblastoma

Objective To investigate the clinical,pathological feature and prognosis of lipoblastoma.Methods The clinical date,pathomorphology in 6 cases of lipoblastoma were analyzed,and the literature was reviewed.Results There were 4 males and 2 females.The age is from 5 to 32 months(mean 14.5).The lesions located in the lower limbs is 2 cases,2 in the backs,1 in the upper limbs and 1 in the right mediastinum.All cases were followed-up from 0.5 to 8 years(mean 4).The recurrence was 17%(1/6).The main histopathologic features were lobules of mature and immature fat cells,primitive mesenchymal cells,typical lipoblasts with varying degrees of differentiation,and accompanied with numerous capillaries and varying degree of myxoid matrix.Conclusion Lipoblastoma is a rare benign tumor,although some tumors present local recurrence.The treatment of lipoblastoma is local excision.It needs to be differentiated from myxoid liposarcoma.