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肝癌内分泌分化的免疫组织化学研究
引用本文:崔广林,刘益清.肝癌内分泌分化的免疫组织化学研究[J].河南医学研究,1994,3(2):145-147.
作者姓名:崔广林  刘益清
作者单位:河南医科大学第二附属医院消化内科,民权县公疗医院
摘    要:本文应用嗜银染色和免疫组织化学方法对34例原发性肝癌(肝细胞肝癌28例,胆管细胞型肝癌6例)组织及癌旁组织中的内分泌细胞进行了研究;结果显示:内分泌细胞阳性率为11.76%(肝细胞肝癌3例,胆管细胞型肝癌1例);在癌旁组织中也发现两例异位胃泌素阳性细胞。本文结果提示:①肝癌组织中存在内分泌细胞的分化;②癌旁组织中发现异位胃泌素阳性细胞的表达。

关 键 词:原发性肝癌,内分泌细胞,免疫组织化学方法

IMMUNOHISTOCHEMICAL STUDY OF ENDOCRINE DIFFERENTIATION IN PRIMARY LIVER CANCER
Cui Guang-lin Liu Yi-qing Yuan Wei-xian.IMMUNOHISTOCHEMICAL STUDY OF ENDOCRINE DIFFERENTIATION IN PRIMARY LIVER CANCER[J].Henan Medical Research,1994,3(2):145-147.
Authors:Cui Guang-lin Liu Yi-qing Yuan Wei-xian
Abstract:Endocrine cells were studied in 34 cases of primary liver cancer(28 cases ofhepatocarcinoma,6 cases of cholangiocarcinoma)tissue and adjacent tissue by Grimelius sil-ver stain and immunohistochemistry. The results showed that:Endocrine cells were found in11.74%(4/34)primary liver cancer tissue(3 cases of hepatocarcinoma,one cases of cholan-giocarcinoma),ectopic gastrin producing cells were found in 2 cases of adjacent tissue of pri-mary liver cancer.The finding suggest that:①Engocrine differentiation was found in primary liver can-cer;②Expresion of ectopic gastrin producing cells were found in adjacent tissue.
Keywords:primary liver cancer  endocrine cell  immunohistochemistry
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