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Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action |
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| Authors: | Ichiro Kawahata Masaaki Yoshida Wen Sun Akira Nakajima Yanxin Lai Naoya Osaka Kentaro Matsuzaki Akihito Yokosuka Yoshihiro Mimaki Akira Naganuma Yoshihisa Tomioka Tohru Yamakuni |
| Institution: | 1. Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki Aoba-ku, Sendai, 980-8578, Japan 2. Research Laboratory, Kotaro Pharmaceutical Co., Ltd, Ro 96-1 Kashima-machi, Hakusan, Ishikawa, 920-0201, Japan 7. Department of Neuropsychopharmacology and Hospital Pharmacy, School of Medicine, Nagoya University, Tsuruma-cho, Showa-ku, Nagoya, 466-8560, Japan 3. Department of Environmental Physiology, Faculty of Medicine, Shimane University, 89-1 Shioya, Izumo-shi, Shimane, 693-8501, Japan 4. Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, 192-0392, Japan 5. Department of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, 980-8578, Japan 6. Department of Oncology, Pharmacy Practice and Sciences, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, 980-8578, Japan |
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