妊娠期糖尿病的治疗对母婴结局的影响

目的探讨妊娠期糖尿病的治疗对母婴结局的影响，进一步指导临床。方法选取该院2006年1月-2012年12月收治入院的妊娠期糖尿病产妇300例，按照随机对照原则，将患者分为观察组和对照组两组，每组各150例，其中150例患者在怀孕期间确诊为妊娠期糖尿病并予以治疗的作为观察组，其余的150例患者在临产后或发生并发症后确诊为妊娠期糖尿病患者作为对照组，分析两组孕产妇和围生儿结局有无差异。结果观察组孕产妇发生妊娠期高血压疾病、羊水过多、胎膜早破、早产、剖宫产等情况的发生率明显高于对照组，差异有统计学意义（P〈0．05）；观察组围生儿发生胎儿窘迫、新生儿窒息、新生儿低血糖、巨大儿等情况的发生率也明显高于对照组，差异有统计学意义（P〈0．05）。结论妊娠期糖尿病能够明显增加母婴并发症的发生率，因此要对其进行早期诊断和规范化的治疗，适时终止妊娠可以有效的降低母婴并发症的发生。

The Effect of the Treatment of Gestational Diabetes Mellitus on Maternal- infant Outcome

Objective To investigate the effect of the treatment of gestational diabetes mellitus on maternal-infant outcome so as to further guide the clinical work. Methods 300 cases of puerperants with gestational diabetes admitted in our hospital from January, 2006 to December, 2012 were selected and randomly divided into the observation group and the control group with 150 cases in each, the 150 patients who were diagnosed as gestational diabetes mellitus and given treatment were selected as the observation group, and the other 150 patients diagnosed as gestational diabetes mellitus after labor or having complications were selected as the control group. And the maternal and perinatal outcomes of two groups were analyzed. Results The incidences of hypertension during pregnancy, hydramnion, premature rupture of fetal membranes, premature birth, cesarean section and so on of the puerperants in the observation group were significantly higher than those of the puerperants in the control group, the differences were statistically significant（P 〈 0.05）; the incidences of fetal distress, asphyxia neonatorum, neonatal hypoglycemia, macrosomia and so forth of the perineonates in the observation group were obviously higher than those of the perineonates in the control group, the differences were statistically significant（P 〈 0.05）. Conclusion Gestational diabetes can significantly increase the incidence of complications of mothers and infants, therefore early diagnosis and standard treatment and timely termination of pregnancy can effectively reduce the incidence of complications of mothers and infants.