| 丙肝基因分型研究 |
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| 引用本文： | 何平,陈春勇. 丙肝基因分型研究[J]. 医药论坛杂志, 2010, 31(2): 10-11 |
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| 作者姓名： | 何平 陈春勇 |
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| 作者单位： | 郑州大学第一附属医院感染科,郑州市,450052;郑州市疾病预防控制中心,郑州市,450053 |
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| 摘 要： | 目的了解河南地区不同丙型肝炎病毒(HCV)基因型的分布特点,对病情及抗病毒的疗效进行预测。方法应用逆转录-聚合酶链反应(RT-PCR)技术对丙肝患者进行HCVRNA定量检测,对60例HCVRNA阳性标本应用PCR进行HCV基因分型。采用SPSS10.0进行统计学分析。结果60例HCVRNA阳性的丙肝患者中,1b型46例,占77%,2a型为14例,占23%。结论河南地区HCV感染者中以1b型为主,对HCV感染者在治疗前进行有效的疗效预测具有重要的临床意义。
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| 关 键 词： | 丙型肝炎病毒(HCV) 基因型 聚合酶链反应 |
Research on HCV Genotyping |
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| HE Ping,CHEN Chunyong. Research on HCV Genotyping[J]. Journal of Medical Forum, 2010, 31(2): 10-11 |
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| Authors: | HE Ping CHEN Chunyong |
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| Affiliation: | HE Ping,CHEN Chunyong Department of Infectious Diseases,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China |
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| Abstract: | Objective To understand the different hepatitis C virus in Henan region HCV genotype distribution,and on the condition and to predict the efficacy of anti - virus.Methods Reverse transcription - polymerase chain reaction(RT - PCR) technique for quantitative detection of hepatitis C patients HCVRNA,60 cases of HCV - RNA positive samples were applied to HCV genotyping PCR.SPSS10.0 used for statistical analysis.Results 60 cases of HCVRNA positive hepatitis C patients,1b -type 46 cases,accounting for 77%,2a - t... |
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| Keywords: | Hepatitis C Virus Genotype Polymerase chain reaction |
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