首页 | 本学科首页   官方微博 | 高级检索  
检索        

配比油对家兔体内抗氧化酶类活性的影响
引用本文:孙树秦,谭亚芳,陈镇童,赖炳森.配比油对家兔体内抗氧化酶类活性的影响[J].基础医学与临床,2003,23(1):97-100.
作者姓名:孙树秦  谭亚芳  陈镇童  赖炳森
作者单位:解放军北京军医学院生物化学教研室,全军超临界萃取技术重点实验室,北京,100071
基金项目:解放军“九五”医药卫生基金 (96D0 6 9)
摘    要:观察不同配比n-3,n-6系脂肪酸的配比油对家兔体内几种抗氧化酶活性的影响,实验用家兔,共50只随机分为5组。对照组喂饲基础饲料,高脂组喂饲富含猪油和胆固醇(Ch)的饲料,配比油组(配比1组。配比2组,配比3组)喂饲的饲料中除了猪油和胆固醇外,还有不同配比n-3,n-6系脂肪酸的配比油,实验三个月中每间隔一个月耳缘静脉取血一次,检测各组家兔红细胞中超氧化物歧化酶(SOD)。过氧化氢酶(CAT),谷胱甘肽过氧化物酶9GSH-Px)。活性的变化,结果表明配比油使SOD,CAT活性均明显增强,但不同油脂对GSH-Px活性的影响较复杂,说明不同配比n-3,n-6系脂肪酸的混合油均可增强抗氧化系统酶活性,其增强作用与不同配比剂量密切相关。

关 键 词:多烯脂酸  SOD  CAT  GSH-Px  动脉粥样硬化
文章编号:1001-6325(2003)01-0097-04

Effect of formulated oil with polyunsaturated fatty acids on antioxidation enzymes activities in rabbit
SUN Shu qin,TAN Ya fang,CHEN Zhen tong,et al..Effect of formulated oil with polyunsaturated fatty acids on antioxidation enzymes activities in rabbit[J].Basic Medical Sciences and Clinics,2003,23(1):97-100.
Authors:SUN Shu qin  TAN Ya fang  CHEN Zhen tong  
Institution:SUN Shu qin,TAN Ya fang,CHEN Zhen tong,et al .
Abstract:To study the effects of mixed oil with different dietary n 3 and n 6 long chain polyunsaturated fatty acids content on several antioxidation enzymes activities such as SOD, CAT, GSH Px. 50 rabbits were randomLy divided into 5 groups: control group(fed with basic food),high fat group(fed with basic food and lard)and three different groups of mixed oil respectively(MOG1, MOG2,MOG3,fed with basic food and mixed oil respectively). SOD,CAT, GSH Px activities of RBC were analyzed every month during an experimental period of 3 months. SOD and CAT activities increased significantly, while GSH Px activities had complicated changes with different fatty acids content. All the mixed oil had antioxidation capacity and increased antioxidation enzymes' activities. The different fatty acids content influences the antioxidation capacity.
Keywords:polyunsaturated fatty acids  SOD  CAT  GSH  Px  atheromatosis
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号