Parry-romberg综合征的临床及影像学特征——文献复习并1例报告

目的探讨Parry-romberg综合征的临床及影像学特征,以提高对本病的认识。方法对一例Parry-romberg综合征患者的临床、头部CT、MRI影像学进行分析,并对患者进行随访。结果患者以癫痫起病,左侧面部萎缩,头部CT可见左侧枕叶钙化灶,头部MRI示左侧基底节、颞枕叶白质片状T1低信号T2高信号,MRI梯度回波T2＊示左侧多发小点状病灶提示微出血,随访发现患者左侧面部萎缩进行性加重,头部MRI可见原有脑部病灶处小圆囊性改变。结论Parry-romberg综合征是一种少见病,可以合并神经系统症状,临床表现结合影像学有利于诊断。

The clinical manifestations and imaging findings in a patient with Parry-romberg syndrome(a case report and literature review)

Objective To investigate the clinical features and imaging findings of Parry-romberg syndrome and to elevate recognization for this rare disease. Methods The clinical features and imaging findings of Computed tomography （CT） and Magnetic resonance imaging （MRI） were analyzed in one patient with Parry-romberg syndrome and follow-up of this patient. Results The clinical manifestations of onset of this patient were epilepsy with left facial atrophy, cranial CT shows the calcification of the left occipital lobe, the MRI scan demonstrated T1 and T2 prolongation in left basal ganglia and in the white matter in the temporal and occipital region of the left hemisphere, T2＊-weighted gradient-echo MRI image shows scattered microhemorrhages in left hemisphere. Progressive atrophy in the face and the small cystic lesions in MRI were found in the follow-up. Conclusion Parry-romberg syndrome is a rare disease, neurological symptoms can appear in the Parry-romberg syndrome. The diagnosis depends on the clinical manifestations and imaging findings.