芍药汤加味联合奥沙拉秦钠治疗湿热内蕴型活动期溃疡性结肠炎对照研究

[目的]观察芍药汤加味联合奥沙拉秦钠治疗湿热内蕴型活动期溃疡性结肠炎疗效。[方法]将40例门诊患者随机数字表法分为两组。对照组20例奥沙拉秦钠1g/次,2次/d,饭后口服。治疗组20例奥沙拉秦钠治疗同时加用芍药汤加味(白芍20g,黄芩15g,黄连9g,黄柏15g,大黄3g,槟榔9g,当归12g,木香12g,肉桂3g,甘草6g)1剂/d。均治疗6周,随访12月判定疗效。[结果]治疗组完全缓解12例,有效8例,无效0例,总有效率100.00%。对照组完全缓解10例,有效7例,无效3例,总有效率85.00%。临床疗效治疗组优于对照组(P<0.05),主要症状及结肠镜检有效率治疗组优于对照组(P<0.05)。[结论]芍药汤加味联合奥沙拉秦钠治疗湿热内蕴型活动期溃疡性结肠炎疗效优于单用奥沙拉秦钠,值得推广。

Shaoyao Decoction with Olsalazine Sodium in the Treatment of Damp and Activity of Ulcerative Colitis Control Study

[ Objective] To observe the efficacy of Shaoyao decoction with inner heat olsalazine sodium treatment of active ulcerative colitis. [ Method] 40 outpatients randomly divided into two groups. Control group of 20 cases of olsalazine sodium 1 g / 2 times / d, oral after a meal. Olsalazine sodium in the treatment, the treatment group, 20 cases were added Shaoyao decoction （Baishao 20g, Huangqin 15g, Huanglian 9g, Huangbai 15g, Dahuang 3g, Binlang 9g, Danggui 12g, Muxiang 12g, Rougui 3g, Gancao 6g） 1 time / day. 6 weeks of treatment, followup in December to determine efficacy. [ Results] The complete remission in 12 cases, eight cases effectively, and 0 cases, the total efficiency of 100.00%. Control group, complete remis- sion in 10 cases, effective in 7 cases, 3 cases, the total efficiency of 85.00%. The clinical efficacy of the treatment group than the control group （ P 〈 0.05） , the main symptom and colonoscopy the efficiency of the treatment grouD than the control group （ P 〈 0. 05）. F Conclusion7 peony Decoction ioint olsalazine sodium in the treatment of damp and activity of ulcerative colitis effective than single olsalazine worthy of promotion.