1 566例氢氟酸灼伤病例临床分析

目的 探索氢氟酸灼伤创面治疗的有效手段,为氢氟酸灼伤的临床救治提供参考。 方法 电子检索2002年8月到2012年7月同方知网全文数据库、万方数字化期刊数据库、维普科技期刊数据库及中国生物医学文献数据库,收集氢氟酸灼伤病例,筛选后进行数据提取。统计学分析采用SPSS 16.0软件。 结果 共收录54篇文献(1 566例)。二分类Logistic回归分析表明,现场冲洗、糖皮质激素的应用对于氢氟酸灼伤的治疗有积极作用,男性为氢氟酸灼伤完全治愈的保护因素,伤后3 d后入院为危险因素。 结论 对于发生灼伤的病人,应重视现场洗消和早期急救处理,及时使用弱碱并早期快速大剂量补钙,避免低血钙症和心率失常等并发症的发生是治疗的关键,糖皮质激素的应用对于氢氟酸灼伤的治疗有积极作用。

Clinical analysis of 1566 hydrofluoric acid burn cases

Objective The objectives of this study are to investigate the effective treatment methods of hydrofluoric acid burn wounds, and provide a reference for the clinical treatment of hydrofluoric acid burns. Methods Hydrofluoric acid burn cases were collected by searching the Tongfang full-text database, Wanfang digital periodical database, VIP science and technology periodical database and China Biological and Medical Journal Full-text database between August of 2002 and July of 2012. The data were extracted after screening. The statistical data were analyzed using SPSS 16.0 software. Results A total of 54 articles (1 566 cases) were included in the study. Binary classification logistic regression analysis showed that immediate washing and application of glucocorticoid hormones played positive roles in the treatment of hydrofluoric acid burn. The gender male was a protective factor for the complete cure of hydrofluoric acid burn. Admission to hospitals 3 days after burn was a risk factor. Conclusion For patients suffering from burn, it should be paid more attention to immediate flush and early emergency treatments, timely application of weak bases and rapidly complement large doses of calcium in the early stages. Avoiding the occurrence of hypocalcemia, arrhythmic and other complications was a key during the treatments, and applications of glucocorticoid had positive effects for the treatment of hydrofluoric acid burns.