Preliminary study on the nucleic acid hybridization technic in detecting HSV-2 DNA corresponding sequence of cancer tissues of the uterine cervix |
| |
| Authors: | H Y Cui W Zhang J Li B Y Liu J S Li Y C Lin W H Zhang A R Wu Z M Liu |
| |
| Institution: | Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing. |
| |
| Abstract: | In this paper, 34 samples, 25 from 18 cervical carcinoma patients and 9 from 8 non-cervical carcinoma patients, were assayed using (alpha-32P) dCTP HSV-2 DNA probe and nucleic acid hybridization technic. It was shown that the positive rates of HSV-2 DNA corresponding sequence were 50% (2/4), 36% (5/14) and 12% (1/8) in the in situ cancer, invasive cancer and non-cervical cancer tissues. No HSV was isolated from 7 cancer specimens which showed a positive reaction by nucleic acid hybridization. |
| |
| Keywords: | |
|
|
