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| 重型颅脑损伤患者血清NSE检测及其临床意义 | |
| 引用本文： | 李俊,刘红朝,张刚利,谢蕊繁,郭东生,雷霆.重型颅脑损伤患者血清NSE检测及其临床意义[J].华中科技大学学报(医学版),2011,40(2):225-228. |
| 作者姓名： | 李俊 刘红朝 张刚利 谢蕊繁 郭东生 雷霆 |
| 作者单位： | 1. 武汉市中心医院神经外科,武汉,430012 2. 华中科技大学同济医学院附属梨园医院神经外科,武汉,430077 3. 山西省人民医院神经外科,太原,030012 4. 华中科技大学同济医学院附属同济医院神经外科,武汉,430030 |
| 基金项目： | 湖北省卫生厅科技攻关资助项目 |
| 摘 要： | 目的 探讨血清神经元特异性烯醇化酶(NSE)作为重型颅脑损伤患者神经损伤特异标志物的可行性.方法 选取96例重型颅脑损伤患者(GCS≤8)和25例健康体检者作为研究对象,入院时,按格拉斯哥昏迷评分(GCS)将患者分为特重型组(GCS 3～5分)和重型组(GCS 6～8分);按CT检查结果将患者依损伤类型分为3组:脑挫裂... |
| 关 键 词： | 重型颅脑损伤 神经元特异性烯醇化酶 格拉斯哥昏迷评分 |
Determination of Serum Neuron-specific Enolase in Patients with Severe Traumatic Brain Injury |
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| Li Jun,Liu Hongchao,Zhang Gangli et al.Determination of Serum Neuron-specific Enolase in Patients with Severe Traumatic Brain Injury[J].Journal of Huazhong University of Science and Technology(Health Sciences),2011,40(2):225-228. | |
| Authors: | Li Jun Liu Hongchao Zhang Gangli |
| Institution: | Li Jun1,Liu Hongchao2,Zhang Gangli3 et al 1Department of Neurosurgery,Central Hospital of Wuhan,Wuhan 430012,China 2Department of Neurosurgery,Liyuan Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430077,China3Department of Neurosurgery,Shanxi Provincial People's Hospital,Taiyuan 030012,China |
| Abstract: | Objective To determine the concentration of serum neuron-specific enolase(NSE)as a specific marker of nerve injury in patients with severe traumatic brain injury(TBI).Methods Ninety-six patients with severe TBI were included and 25 healthy volunteers were recruited as controls in the study.According to evaluation by the Glasgow Coma Scale(GCS)at admission,severe TBI patients were divided into two groups,GCS 3-5 severe TBI group and GCS 6-8 severe TBI group.According to the CT findings at admission,severe TB... |
| Keywords: | severe traumatic brain injury neuron-specific enolase Glasgow Coma Scale |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |