| 儿童脑梗死后Wallerian变性的磁共振弥散张量成像研究 |
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| 引用本文： | 顾晓丽,周林江,李克,沈天真,陈星荣. 儿童脑梗死后Wallerian变性的磁共振弥散张量成像研究[J]. 中国医学计算机成像杂志, 2005, 11(6): 367-369 |
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| 作者姓名： | 顾晓丽 周林江 李克 沈天真 陈星荣 |
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| 作者单位： | 1. 313000,浙江省湖州市中心医院放射科
2. 复旦大学附属华山医院放射科 |
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| 摘 要： | 目的:研究应用磁共振弥散张量成像(DTI)检测和定量分析儿童脑梗死后皮质脊髓束Wallerian变性的可行性.材料和方法:对11例单侧大脑中动脉供血区脑梗死的患儿进行了DTI研究.通过放置兴趣区(ROI)的方式获得定量部分各向异性(FA)和平均弥散量(MD).ROI放置的部位包括:脑梗死区、脑梗死同侧内囊后支和大脑脚,以及上述部位对侧相应区域.应用Marn-Whitney U检验确定差异有无显著性.结果:脑梗死同侧皮质脊髓束FA较对侧明显下降(P=0.05),但MD改变无明显差异.结论:应用FA,DTI可以检测并定量分析儿童脑梗死后皮质脊髓束Wallerian变性.
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| 关 键 词： | 脑梗死 Wallerian变性 弥散张量成像 |
Evaluation of Wallerian Degeneration in Paediatric Infarction Using Diffusion-tensor MR Imaging |
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| Gu Xiaoli, Zhou Linjiang, Li Ke, et al. Evaluation of Wallerian Degeneration in Paediatric Infarction Using Diffusion-tensor MR Imaging[J]. Chinese Computed Medical Imaging, 2005, 11(6): 367-369 |
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| Authors: | Gu Xiaoli Zhou Linjiang Li Ke et al |
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| Abstract: | Purpose:To evaluate DTI,using fractional anisotropy(FA)and mean diffusivity(MD),can detect and quantify Wallerian degeneration in pediatric infarction.Materials and Methods:Eleven children with unilateral MCA infarction were recruited.Quantitative FA and MD,obtained by manually placing re-gions-of-interest(ROI)within the infarction,and along the ipsilateral corticospinal tract,i.e.the posterior limb of the internal capsule and cerebral peduncle,were compared with matched contralateral regions using the Mann-Whitney U-test.Results:The FA,but not the MD,of the ipsilateral corti-cospinal tract was significantly different compared to the normal side(P=0.05).Conclusion:DTI,using FA,can detect and quantify WD in paediatric infarction. |
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| Keywords: | Infarction Wallerian degeneration Diffusion-tensor MR imaging |
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