| 鬼臼毒素涂膜剂的制备及质量控制 |
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| 引用本文： | 曹健,钟惠平,李进.鬼臼毒素涂膜剂的制备及质量控制[J].中国药房,2001,12(10):594-595. |
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| 作者姓名： | 曹健 钟惠平 李进 |
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| 作者单位： | 第三军医大学新桥医院药剂科, |
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| 摘 要： | 目的 :研究鬼臼毒素涂膜剂的制备及其质量控制方法。方法 :采用正交函数法筛选鬼臼毒素涂膜剂的处方 ,二阶导数紫外分光光度法对其进行含量测定。结果 :所选处方的鬼臼毒素在80～180μg/ml范围内 ,浓度与二阶导数光谱301 5nm～315nm波长处的峰面积呈线形关系 ,C=1052 41Au—8 74 ,r=0 9999。结论 :鬼臼毒素涂膜剂的制备工艺简单 ,质量控制方法可行
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| 关 键 词： | 鬼臼毒素 涂膜剂 制备 质量控制 |
| 文章编号： | 1001-0408(2001)10-0594-02 |
| 修稿时间： | 2001年1月19日 |
Preparation and Quality Control of Podophyllotoxin Film Former |
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| CAO Jian,ZHONG Huiping,LI Jin.Preparation and Quality Control of Podophyllotoxin Film Former[J].China Pharmacy,2001,12(10):594-595. |
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| Authors: | CAO Jian ZHONG Huiping LI Jin |
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| Abstract: | OBJECTIVE:To investigate the preparing process and method of quality control of the podophyllotoxin film former METHODS:To sift the formula of podophyllotoxin film former with orthogonal function and to determine the content by second derivative UV-spectrophotometry RESULTS:The peak area of podophyllotoxin against the concentration was linear with a correlation coefficient of 0 9 999 over the range of 80～180μg/ml and detecting at wavelength 301 5nm～315nm CONC_LUSION:The preparing process of podophyllotoxin film former is simple and the method of quality control is feasible |
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| Keywords: | podophyllotoxin film former preparation quality control |
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