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类固醇激素合成急性调节蛋白(StAR)与胆固醇代谢
引用本文:许雅丽,殷莲华.类固醇激素合成急性调节蛋白(StAR)与胆固醇代谢[J].国际病理科学与临床杂志,2008,28(4):18-361.
作者姓名:许雅丽  殷莲华
作者单位:复旦大学上海医学院生理与病理生理学系,上海,200032
摘    要:类固醇激素合成急性调节蛋白(StAR)在胆固醇的代谢中发挥重要的作用。近期研究表明StAR同样表达于肝脏组织中,通过调节胆汁酸的合成,增加胆固醇的排泄。这为脂肪肝等脂类代谢异常类疾病的防治提供了一条新的途径。

关 键 词:类固醇激素合成急性调节蛋白  胆汁酸合成  胆固醇转运
收稿时间:2008-3-3
修稿时间:2008-4-15

Steroidogenic acute regulatory protein (StAR) and cholesterol metabolism
XU Ya-li,YIN Lian-hua.Steroidogenic acute regulatory protein (StAR) and cholesterol metabolism[J].Journal of International Pathology and Clinical Medicine,2008,28(4):18-361.
Authors:XU Ya-li  YIN Lian-hua
Institution:Department of Physiology and Pathophysiology,Shanghai Medical College of Fudan University,Shanghai 200032,China
Abstract:Steroidogenic acute regulatory protein plays a role in cholesterol metabolism.Recently,researches indicate that it is also expressed in the liver.StAR increases the excretion of cholesterol by regulating the synthesis of bile acid.The findings provide a new way for the prevention and cure of diseases of lipid dysfunction such as hepar adiposum.
Keywords:steroidogenic acute regulatory protein(StAR)  synthesis of bile acid  cholesterol transport
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