Postoperative Results after Desflurane or Sevoflurane Combined with Remifentanil in Morbidly Obese Patients |
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Authors: | Luc E C De Baerdemaeker MD DEAA Stefan Jacobs MD Nadia M M Den Blauwen MD Piet Pattyn MD PhD Luc L G Herregods MD PhD Eric P Mortier MD DSc Michel M R F Struys MD PhD |
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Institution: | (1) Ghent University Hospital, Gent, Belgium;(2) Ghent University Hospital, Gent, Belgium;(3) Ghent University Hospital, Gent, Belgium;(4) Ghent University Hospital, Gent, Belgium;(5) Department of Anesthesia, Ghent University Hospital, Gent, Belgium;(6) Department of Anesthesia, Ghent University Hospital, Gent, Belgium;(7) Department of Anesthesia, Ghent University Hospital, Gent, Belgium; Heymans Institute of Pharmacology, Ghent University, Gent, Belgium |
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Abstract: | Background: This randomized prospective study with blinded postanesthesia care unit (PACU) observers compared the recovery
profiles in morbidly obese patients who received sevoflurane or desflurane for maintenance of anesthesia in combination with
a remifentanil target controlled infusion (TCI). Methods: 50 morbidly obese patients scheduled for laparoscopic gastric banding
were included to receive BIS-guided sevoflurane or desflurane anesthesia with BIS-triggered inhalation boli in combination
with remifentanil TCI. In the PACU, the following recovery scores were investigated: Modified Aldrete score, a modified Observers'
Assessment of Alertness/Sedation Scale (OAA/S), pain numerical rating scale (NRS), oxygen saturation (SpO2) and postoperative nausea and vomiting (PONV). Results: OAA/S and NRS pain scores showed a similar evolution in both groups
from the moment of PACU admission up to 120 minutes after admission. In both groups, patients showed no serious hypoxemia
during PACU stay. Incidence of PONV was shorter lasting in the sevoflurane group compared to the desflurane group. Conclusions:
No clinically relevant difference was found in recovery in the PACU between morbidly obese patients anesthetized with desflurane
or sevoflurane. Both agents resulted in satisfactory recovery in morbidly obese patients. |
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Keywords: | RECOVERY SEVOFLURANE DESFLURANE MORBID OBESITY REMIFENTANIL TCI ANESTHESIA |
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