| 皮肤苔藓样淀粉样变病病理组织化学及超微结构观察 |
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| 引用本文： | 何祖根 王家璧. 皮肤苔藓样淀粉样变病病理组织化学及超微结构观察[J]. 中国医学科学院学报, 1993, 15(2): 115-118 |
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| 作者姓名： | 何祖根 王家璧 |
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| 作者单位： | 中国医学科学院协和医院 北京(何祖根，王家璧，陈新，路英杰)，中国医学科学院协和医院 北京(叶盛芳) |
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| 摘 要： | 10例皮肤苔藓样淀粉样变病病例报告。光学显微镜观察结果表明患处真皮乳头有均匀红染,均质化的球形淀粉样蛋白沉着,并常有裂隙存在;组织化学证实其蛋白类型为淀粉样相关蛋白(amyloid associated,AA);电镜观察证实淀粉样蛋白来源于表皮,形成大小不等之岛状结构,高倍观察淀粉样蛋白由微丝组成。
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| 关 键 词： | 苔藓样淀粉样变病 淀粉样蛋白 微丝 |
Histochemical Studies of Cutaneous Lichen Amyloidosus Using Light and Electron Microscopy |
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| He Zugen,et al. Histochemical Studies of Cutaneous Lichen Amyloidosus Using Light and Electron Microscopy[J]. Acta Academiae Medicinae Sinicae, 1993, 15(2): 115-118 |
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| Authors: | He Zugen et al |
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| Affiliation: | PUMC Hospital |
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| Abstract: | Ten cases of cutaneous lichen amyloidosus are reported. Amyloid deposits were found to be limited to the papillary dermis. The amyloid masses were often fissured and had an amorphous eosinophilic globular appearance. The protein was confirmed by histochemistry as amyloid-associated protein. The epidermal origin of the amyloid deposit has been confirmed by electron microscopy. The amyloid deposit was of variable island structure, accompanied by filaments. |
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| Keywords: | Lichen Amyloidosus AA protein filament |
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