| 川芎嗪的体内代谢 |
| |
| 引用本文： | 江骥 姜国辉. 川芎嗪的体内代谢[J]. 中国医学科学院学报, 1993, 15(2): 79-82 |
| |
| 作者姓名： | 江骥 姜国辉 |
| |
| 作者单位： | 中国医学科学院协和医院 北京(江骥，姜国辉，叶云鹏)，中国医学科学院协和医院 北京(王世真) |
| |
| 基金项目： | 国家自然科学基金，卫生部科研基金资助 |
| |
| 摘 要： | 本研究使用氘代川芎嗪(TMPz)为示踪剂,结合稳定同位素和GC/MS分析的离子簇技术,发现接受灌胃给予TMPz后大鼠的24h尿中存在有TMPz本身及其三种代谢产物.
|
| 关 键 词： | 川芎嗪 稳定同位素 气相层析/质谱联用仪 代谢产物 离子簇技术 |
The Metabolism of TMPz In Vivo |
| |
| Jiang Ji,et al. The Metabolism of TMPz In Vivo[J]. Acta Academiae Medicinae Sinicae, 1993, 15(2): 79-82 |
| |
| Authors: | Jiang Ji et al |
| |
| Abstract: | The metabolism of tetramethylpyrazine (TMPz) in rats was investigated. Deuterated TMPz and unlabelled TMPz were administered by intragastric per-fusion to two rats, respectively. Extracts from urine samples were analyzed within 24h by gas chromatography/mass spectrometry (GC/MS). By applying the ion cluster technique, TMPz and its three metabolites were identified. |
| |
| Keywords: | tetramethylpyrazine (TMPz) stable isotope gas chromatograph-y/mass spectrometry GC/MS metabolites ion cluster technique |
| 本文献已被 CNKI 维普 等数据库收录！ |
