中药血清与肝星状细胞研究进展

肝星状细胞（hepatic stellate cells，HSCs）的活化、增殖是肝纤维化形成和发展的中心环节。利用中药血清药理学研究方法发现，中药血清可干预肝纤维化形成和发展。综述了中药血清与肝星状细胞的研究进展，指出中药血清从抑制HSCs活化、HSCs增殖、HSCs收缩，促进HSCs凋亡等多靶点作用于肝星状细胞。可能是一种有效的抗肝纤维化治疗方法。

Progress of Research on Chinese Material Medica Serum and Hepatic Stellate Cells

The activation and proliferation of hepatic stellate cells (HSCs) is the central link in the formation and progression of liver fibrosis. From the research of serum pharmacological method of Chinese material medica, we found Chinese material medica serum could interfere in the formation and progression of liver fibrosis. This paper reviewed the progress on Chinese material medica serum and HSCs. The authors pointed out Chinese material medica serum could effect on the activation, proliferation, contraction and apoptosis of HSCs, which probably is an effective therapy for liver fibrosis.