丙泊酚在重型颅脑损伤患者急症手术的麻醉效果

目的观察丙泊酚在全麻时对重型颅脑损伤患者的影响,以提高麻醉技术。方法分析52例采用快速静脉诱导气管内插管,丙泊酚微量泵静注复合全麻的重型颅脑损伤手术患者的临床资料。结果全组病例麻醉管理中无呕吐、误吸,麻醉效果好,无麻醉死亡;术中、平均动脉压、心率等血流动力学参数虽与术前有显著差异,但绝大部分值均在正常范围。结论丙泊酚微量泵静注复合全麻是重型颅脑损伤患者行急诊手术安全有效的麻醉方法。

Effect of Propofol in Anaesthesia of Emergency Operation for Patients with Severe Brain Injury

Objective To evaluate the effect of propofol in anaesthesia of emergency operation for patients with severe brain injury. Methods 52 patients with severe brain injury received endotracheal intubation after intravenous induction and were exposed to propofol of 4 -8 mg/（ kg · h） for maintenance of anesthesia, with intermittent intravenous injection of veeuronium and fentanyl, Results Vomiting and aspiration were absent in entire group during anaesthesia with favorable anaesthesia effect and without death from anaesthesia. There were substantial differences in hemodynamics parameters such as MAP and HR compared to that before operation, but was still within normal range for most parameters. Conclusions Continuous intravenous infusion of propofol combined with vecuronium and fentanyl for anaesthesia induction is a safe and potent method for anesthesia in severe brain injury patients undergoing emergency surgery.