| Abstract: | The relationships between two skin physiological factors and skin susceptibilities were investigated in 101 healthy Japanese females. Skin color and skin surface lipids chosen as the factors to be considered were measured by spectrophotometric colormeter and gravimetry, respectively. Photosensitivity was evaluated by minimal erythemal dose (MED) measurements. Skin susceptibility to irritants was evaluated by the patch test method using propylene glycol solution. The results were obtained as follows. (1) A significant correlation was found between skin color V values and photosensitivity scores. (2) A significant inverse correlation was found between skin color V values and replacement lipid values. (3) A correlation was observed between skin color V values and skin irritability scores. (4) A correlation was observed between skin irritability and photosensitivity scores. Thus, skin color and skin surface lipids were shown to be important physiological factors in skin susceptibility to UV irradiation and irritants. |
