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Haemorrhagic presentation of low-grade glioma in adults
Authors:A. Della Puppa  F. Zustovich  M. Gardiman  R. Manara  D. Cecchin  R. Scienza
Affiliation:(1) Department of Neurosurgery, Padua Hospital, Padua, Italy;(2) Department of Oncology, I.O.V.-I.R.C.C.S, Padua, Italy;(3) Department of Pathology, Padua Hospital, Padua, Italy;(4) Department of Neuroradiology, Padua Hospital, Padua, Italy;(5) Department of Diagnostic Medical Sciences, Nuclear Medicine Service, University Hospital, Padua, Italy
Abstract:Summary Intracranial bleeding is rare in patients with low-grade gliomas, above all in adult population. We reviewed the literature of such cases and reported another case of a haemorrhagic low-grade glioma in a 54-year-old woman presenting with a left hemiparesis. Computer tomography (CT) images showed a right basal ganglia haemorrhage with no mass effect. Vascular malformations were ruled out by angiography. Eighteen fluoro–fluoro deossiglucosio (18F-FDG) positron emission tomography (PET/CT) showed a large hypometabolic area corresponding to the lesion. We waited for patient’s improvement. Late magnetic resonance images revealed a low-grade glioma at the bleeding site. Tumour was removed and histopathologic examination revealed a WHO grade II mixed glioma. The authors emphazise that this evidence has to be kept in mind since it has important therapeutic implications.
Keywords:: Low-grade gliomas   mixed gliomas   intratumoural bleeding.
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