Diffusion weighted imaging and neuropsychological correlates in adults with mild traumatic brain injury |
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| Authors: | David B. FitzGerald Bruce A. Crosson |
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| Affiliation: | a Neurology Service/127, North Florida/South Georgia Veterans Health System, 1601 SW Archer Road, Gainesville, FL 32608-1197, United Statesb Brain Rehabilitation Research Center, Rehabilitation Research and Development Service (RR&D), Office of Research and Development, Department of Veteran Affairs, United Statesc Department of Neurology, P.O. Box 100236, University of Florida, Gainesville, FL 32610-0236, United Statesd Department of Clinical and Health Psychology, P.O. Box 100185, University of Florida, Gainesville, FL 32610-0185, United States |
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| Abstract: | Diffusion Tensor Imaging (DTI) is increasingly being used as a research tool in mild Traumatic Brain Injury (mTBI). This article reviews the concepts of diffusion tensor imaging, neuropsychological testing and results to date when applied to mTBI in adults. DTI is being used in conjunction with neuropsychological and electrophysiological measures to provide improved structural/functional correlations of mTBI. Future directions and applications of DTI in mTBI research are suggested. |
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| Keywords: | ADC, Apparent Diffusion Coefficient AN, anterior nucleus of the thalamus ANT, Attention Network Test CPT, Continuous Performance Test CT, Computed axial Tomography CVLT, California Verbal Learning Test DTI, Diffusion Tensor Imaging DWI, Diffusion Weighted Imaging FA, Fractional Anisotropy FLAIR, FLuid Attenuated Inversion Recovery sequence fMRI, functional Magnetic Resonance Imaging GCS, Glascow Coma Score LDFR, Long Delay Free Recall subtest of the CVLT MD, Mean Diffusivity MRI, Magnetic Resonance Imaging mTBI, mild Traumatic Brain Injury NSI, Neurobehavioral Symptom Inventory NVSRT, Non Verbal Selective Reminding Test PCL-C, PTSD Check List Civilian PCS, Post Concussive Syndrome PTA, Post Traumatic Amnesia PTSD, Post Traumatic Stress Disorder ROI, Regions of Interest SDFR, Short Delay Free Recall subtest of the CVLT SWI, Susceptibility Weighted Imaging VA, Ventral Anterior nucleus of the thalamus VL, Ventral Lateral nucleus of the thalamus voxel, Volume Element VSRT, Verbal Selective Reminding Test |
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