Secondary radiation doses of intensity-modulated radiotherapy and proton beam therapy in patients with lung and liver cancer |
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Authors: | Seonkyu KimByung Jun Min Myonggeun Yoon Jinsung KimDong Ho Shin Se Byeong LeeSung Yong Park Sungkoo ChoDae Hyun Kim |
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Affiliation: | a Proton Therapy Center, National Cancer Center, Goyang, Republic of Korea b Department of Radiological Science, Yonsei University, Wounju, Republic of Korea c Department of Radiation Oncology, Samsung Medical Center, Seoul, Republic of Korea |
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Abstract: | PurposeTo compare the secondary radiation doses following intensity-modulated radiotherapy (IMRT) and proton beam therapy (PBT) in patients with lung and liver cancer.Methods and materialsIMRT and PBT were planned for three lung cancer and three liver cancer patients. The treatment beams were delivered to phantoms and the corresponding secondary doses during irradiation were measured at various points 20-50 cm from the beam isocenter using ion chamber and CR-39 detectors for IMRT and PBT, respectively.ResultsThe secondary dose per Gy (i.e., a treatment dose of 1 Gy) from PBT for lung and liver cancer, measured 20-50 cm from the isocenter, ranged from 0.17 to 0.086 mGy. The secondary dose per Gy from IMRT, however, ranged between 5.8 and 1.0 mGy, indicating that PBT is associated with a smaller dose of secondary radiation than IMRT. The internal neutron dose per Gy from PBT for lung and liver cancer, 20-50 cm from the isocenter, ranged from 0.03 to 0.008 mGy.ConclusionsThe secondary dose from PBT is less than or compatible to the secondary dose from conventional IMRT. The internal neutron dose generated by the interaction between protons and body material is generally much less than the external neutron dose from the treatment head. |
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Keywords: | Proton IMRT Neutron Secondary dose |
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